2-Methyl-1,3-propandiol (b-Hydroxyisobutanol)

Applications β-Hydroxyisobutanol is used as a reagent in the synthesis of pyrazolo[1,5-a]pyridinecarbonyl-substituted spirocyclic piperidine ketals as inhibitors of HCV protein NS4B and of hepatitis C viral replication and their lack of cytotoxicity in human cells. References Tai, V.W.-F., et al.: Bioorg. Med. Chem. Lett., 24, 2288 (2014);