2-(Dimethylamino)guanosine-d6

Applications 2-(Dimethylamino)guanosine-d6 is deuterium labeled 2-(Dimethylamino)guanosine (D460850), which can be used to investigate the mechanism of 2'-deoxyoxanosine formation from 2'-deoxyguanosine and nitrous acid. In addition, 2-(Dimethylamino)guanosine can also be employed in mass spectrometry to quantify tRNA modifications related to cellular stress response in Saccharomyces cerevisiae. References Suzuki, T., et al.: Nucleic Acids Res 28, 544 (2000); Chan, C. T. et al.: PLoS Genet 6, e1001247 (2010).