3',5'-Dichloro-2'-hydroxyacetophenone
3',5'-Dichloro-2'-hydroxyacetophenone is a hydrogen bond donor and has a crystal system of orthorhombic. It is soluble in water and insoluble in organic solvents. 3',5'-Dichloro-2'-hydroxyacetophenone binds to the progesterone receptor, which is a nuclear hormone receptor that regulates gene transcription by binding to specific DNA sequences called hormone response elements. There are two cleavage products of progesterone receptor, Malondialdehyde (MDA) and estradiol (E2). 3',5'-Dichloro-2'-hydroxyacetophenone also binds to estrogen receptors, which are proteins located inside or on the surface of cells that bind to hormones and regulate the activity of certain genes. The biochemical function of 3',5'-dichloro-2' hydroxyacetophenone is not well understood but it has been shown to have antioxidant properties.
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